The nonstop is quickest: Delta LGA → DSM (3h 12m), on time 2 times in 3. Southwest via Midway (5h 05m) is more reliable, 82%, but takes 1h 53m longer.
Nonstops (seasonal or thin)
Nonstop details →Best connections, any airlines
Ranked by chance you reach Des Moines on time. Total trip = scheduled departure to arrival, layover included (Des Moines is 1 h behind New York). Layovers up to 4 hours. Pick a connection for the details.
| AmericanDetails → | LGA 06:30 → ORD 08:14AA 462 | 3h 16m Chicago | ORD 11:30 → DSM 13:05AA 4676 · flown by Republic | 7h 35m | 99% | 87% |
| SouthwestDetails → | LGA 06:00 → MDW 07:20WN 2464 | 2h 50m Chicago | MDW 10:10 → DSM 11:30WN 1771 | 6h 30m | 100% | 86% |
| DeltaDetails → | LGA 06:59 → ATL 09:20DL 342 | 3h 05m Atlanta | ATL 12:25 → DSM 13:34DL 2094 | 7h 35m | 99% | 86% |
| SouthwestDetails → | LGA 06:55 → DEN 09:05WN 2454 | 3h 00m Denver | DEN 12:05 → DSM 14:50WN 1524 | 8h 55m | 98% | 85% |
| UnitedDetails → | LGA 10:00 → DEN 12:20UA 716 | 1h 10m Denver | DEN 13:30 → DSM 16:15UA 1311 | 7h 15m | 96% | 84% |
| American + Unitedtwo ticketsDetails → | LGA 07:23 → ORD 09:09AA 392 | 3h 50m Chicago | ORD 12:59 → DSM 14:27UA 1781 | 8h 04m | 99% | 81% |
| UnitedDetails → | LGA 06:00 → IAH 08:44UA 2371 | 3h 11m Houston | IAH 11:55 → DSM 14:10UA 6166 · flown by Mesa | 9h 10m | 98% | 80% |
| DeltaDetails → | LGA 06:00 → ATL 08:15DL 550 | 1h 18m Atlanta | ATL 09:33 → DSM 10:45DL 1704 | 5h 46m | 96% | 79% |
| Tight connection: often missed | ||||||
| UnitedDetails → | LGA 16:59 → DEN 19:35UA 2834 | 1h 10m Denver | DEN 20:45 → DSM 23:44UA 5389 · flown by SkyWest | 7h 45m | 68% | 55% |
| AmericanDetails → | LGA 14:11 → ORD 16:00AA 1705 | 1h 00m Chicago | ORD 17:00 → DSM 18:33AA 4973 · flown by SkyWest | 5h 22m | 66% | 31% |
| AmericanDetails → | LGA 18:00 → DFW 21:06AA 2388 | 59m Dallas-Fort Worth | DFW 22:05 → DSM 23:58AA 1371 | 6h 59m | 46% | 21% |
Same layover, different day-part
How often the first flight arrives too late to connect (45 min minimum), for one-ticket layovers of 45–80 minutes.
Delays build through the day, so an afternoon first leg eats the layover. A short connection is fine early in the morning and a gamble later on.
Mixing airlines
The table above includes two-ticket connections (marked “two tickets”), held to the 90-minute minimum. One ticket only →
Regional partners count as the airline that sells them: SkyWest flying Delta Connection is one Delta ticket.
About this data: US DOT on-time records, Aug 2025 – Jul 2026, all US airlines; regional flights count under the airline that sells them. Schedules (which flights and connections exist, and their times) are as of Jun 6 – Jul 31, 2026; seasonal flights outside that window aren’t ranked. Rebuilt monthly. JSON